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Publications

2006

ARTICLES IN PEER-REVIEWED JOURNALS

Aziz, Z.A., Wells, A.U., Bateman, E.D., Copley, S.J., Desai, S.R., Grutters, J.C., Milne, D.G., Phillips, G.D., Smallwood, D., Wiggins, J., Wilsher, M.L. and Hansell, D.M. 2006. Interstitial lung disease: Effects of thin-section CT on clinical decision making. Radiology, 238(2): 725-733. 

Badri, M., Cleary, S., Maartens, G., Pitt, J.A., Bekker, L.G., Orrell, C.J. and Wood, R. 2006. When to initiate highly active antiretroviral therapy in sub-Saharan Africa? A South African cost-effectiveness study. Antiviral Therapy, 11: 63-72. 

Badri, M., Maartens, G., Mandalia, S., Bekker, L.G., Penrod, J.R., Platt, R.W., Wood, R. and Beck, E.J. 2006. Cost-effectiveness of highly active antiretroviral therapy in South Africa. PLoS Medicine, 3(1): E4. 

Barnes, K.I., Little, F., Smith, P.J., Evans, A., Watkins, W.M. and White, N.J. 2006. Sulfadoxine-pyrimethamine pharmokinetics in malaria: Pediatric dosing implications. Clinical Pharmacology and Therapeutics, 80(6): 582-596. 

Bateman, E.D. 2006. The economic burden of uncontrolled asthma across Europe and the AsiA Pacific region: Can we afford to not control asthma? European Respiratory Review, 15: 1-3. 

Bateman, E.D., Fairall, L.R., Lombardi, D.M. and English, R.G. 2006. Budesonide/formoterol and formoterol provide similar rapid relief in patients with acute asthma showing refractoriness to salbutamol. Respiratory Research, 7(1): 13. 

Bateman, E.D., Izquierdo, J.L., Harnest, U., Hofbauer, P., Magyar, P., Schmid-Wirlitsch, C., Leichtl, S. and Bredenbroker, D. 2006. Efficacy and safety of roflumilast in the treatment of asthma. Annals of Allergy Asthma and Immunology, 96: 679-686. 

Bateman, E.D., Jacques, L., Goldfrad, C., Atienza, T., Mihaescu, T. and Duggan, M. 2006. Asthma control can be maintained when fluticasone propionate/salmeterol in A single inhaler is stepped down. Journal of Allergy and Clinical Immunology, 117(3): 563-570. 

Bateman, E.D., Karpel, J., Casale, T., Wenzel, S. and Banerji, D. 2006. Ciclesonide reduces the need for oral steroid use in adult patients with severe, persistent asthma. Chest, 129: 1176-1187. 

Bekker, L.G., Myer, L., Orrell, C.J., Lawn, S.D. and Wood, R. 2006. Rapid scale-up of A community-based HIV treatment service: Programme performance over 3 consecutive years in Guguletu, South Africa. South African Medical Journal, 96(4): 315-320. 

Benatar, S.R. 2006. Facing ethical challenges in rolling out antiretroviral treatment in resource-poor countries: Comment on "they call it 'patient selection' in Khayelitsha". Cambridge Quarterly of Healthcare Ethics, 15: 322-330.

Benatar, S.R. and Landman, W.A. 2006. Bioethics in South Africa. Cambridge Quarterly of Healthcare Ethics, 15: 239-247. 

Bensimon, C.M. and Benatar, S.R. 2006. Developing sustainability: A new metaphor for progress. Theoretical Medicine and Bioethics, 27(1): 59-79. 

Bheekie, A., Bachman, M., Buskens, I., Allen, S., English, R.G., Mayers, P.M., Fairall, L.R., Majara, B.P., Bateman, E.D. and Zwarenstein, M. 2006. The practical approach to lung health in South Africa (PALSA) intervention: Respiratory guideline implementation for nurse trainers. International Nursing Review, 53): 261-268. 

Bradley, H., Wiysonge, C.S., Volmink, J.A., Mayosi, B.M. and Opie, L.H. 2006. How strong is the evidence for use of beta-blockers as first-line therapy for hypertension? Systemic review and meta-analysis. Journal of Hypertension, 24: 2131-2141. 

Briggs, A.H., Bousquet, J., Wallace, M.V., Busse, W.W., Clark, T.J.H., Pedersen, S.E. and Bateman, E.D. 2006. Cost-effectiveness of asthma control: An economic appraisal of the GOAL study. Allergy, 61(5): 531-536. 

Burch, V. and Benatar, S.R. 2006. Rational planning for health care based on observed needs. South African Medical Journal, 96(9): 796-802. 

Burch, V., Cueto, J., Adnan, N.A.M., Afolabi, B.B., Ismail, Z., Jafri, W., Olapade-Olaopa, E.O., Otieno-Nyunya, B. and Supe, A. 2006. Accreditation of undergraduate Medical training programs: Practices in nine developing countries as compared with the United States. Education for Health: Change in Learning and Practice, 19(2): 207-222. 

Burch, V., Seggie, J.L. and Gary, N.E. 2006. Formative assessment promotes learning in undergraduate clinical clerkships. South African Medical Journal, 96(5): 430-433. 

Burgers, W., Van Harmelen, J.H., Shephard, E.G., Adams, C.H., Mgwebi, T., Bourn, W.R., Hanke, T., Williamson, A.-.L. and Williamson, C. 2006. Design and preclinical evaluation of a multigene human immunodeficiency virus type 1 subtype C DNA vaccine for clinical trial. Journal of General Virology, 87: 399-410. 

Cauchi, J.A., Oliff, S., Baumann, U., Mirza, D., Kelly, D.A., Hewitson, J.P., Rode, H., McCulloch, M., Spearman, W. and Millar, A.J.W. 2006. The Budd-Chiari syndrome in children: The spectrum of management. Journal of Pediatric Surgery, 41: 1919-1923. 

Clausen, T., Romoren, T.I., Ferreira, M., Kristensen, P., Ingstad, B. and Holmboe-ottesen, G. 2006. Chronic diseases and health inequalities in older persons in BotswanA (Southern Africa): A national survey. Journal of Nutrition, Health and Aging, 9(6): 455-461. 

Combrinck, M.I., Willams, J., De Berardinis, M.A., Warden, D., Puopolo, M., Smith, A.D. and Minghetti, L. 2006. Levels of CSF prostaglandin E2, cognitive decline, and survival in Alzheimer's disease. Journal of Neurology Neurosurgery and Psychiatry, 77: 85-88.

Commerford, P.J. 2006. Rationale and design of ACTIVE: The atrial fibrillation clopidogrel trial with irbesartan for prevention of vascular events. American Heart Journal, 151: 1187-1193. 

Commerford, P.J. and Mayosi, B.M. 2006. Acute rheumatic fever. Medicine, 34(6): 239-243. 

Commerford, P.J. and Mayosi, B.M. 2006. An appropriate research agenda for heart disease in Africa. Lancet, 367(9526): 1884-1886. 

Corradi, H.R., Corrigall, A.V., Boix, E., Mohan, C.G., Sturrock, E.D., Meissner, P.N. and Acharya, K.R. 2006. Crystal structure of protoporphyrinogen oxidase from Myxococcus xanthus and its complex with the inhibitor acifluorfen. Journal of Biological Chemistry, 281(50): 38625-38633. 

Dave, J. and Kalula, S.Z. 2006. Preventing fractures in the elderly in GP practice. South African Family Practice, 48(5): 35-41. 

Davids, L.M., Corrigall, A.V. and Meissner, P.N. 2006. Mitochondrial targeting of human protoporphyrinogen oxidase. Cell Biology International, 30: 416-426. 

Davids, V., Hanekom, W.A., Mansoor, N., Gamieldien, H., Gelderbloem, S.J., Hawkridge, A.J., Hussey, G.D., Hughes, E.J., Soler, J., Murray, R.A., Ress, S.R. and Kaplan, G. 2006. The effect of Bacille Calmette-Guerine vaccine strain and route of administration on induced immune responses in vaccinated infants. Journal of Infectious Diseases, 193: 531-536. 

Delany-Moretlwe, S., Gray, G.E., Kagee, A., Myer, L., Puren, A., Ramjee, G., Rees, H., Swartz, L. and Bekker, L.G. 2006. AIDS prevention in South Africa. Southern African Journal of HIV Medicine, 23: 13-17. 

Dhanjal, M., Anthony, J., Owen, E.P., Davidson, J.S. and Rayner, B.L. 2006. Association of pre-eclampsia with the R563Q mutation of the ß-subunit of the epithelial sodium channel. BJOG An International Journal of Obstetrics and Gynaecology, 2006(113): 595-598. 

Du Toit, G., Prescott, R.A., Lawrence, P.R., Johar, A., Brown, G., Weinberg, E.G., Motala, C. and Potter, P.C. 2006. Autoantibodies to the high-affinity IgE receptor in children with chronic urticaria. Annals of Allergy Asthma and Immunology, 96(2): 341-344. 

Eisman, S. 2006. Pruritic papular eruption in HIV. Dermatologic Clinics, 24: 449-457. 

Ekpebegh, C.O. and Levitt, N.S. 2006. A 40 year old woman who developed jaundice during therapy for thyrotoxicosis. PLoS Medicine, 3(1): 42-44. 

Ekpebegh, C.O., Ross, I.L. and Levitt, N.S. 2006. Hyperthyroidism - an unusual feature of thyroid carcinoma. Journal of Endocrinology, Metabolism and Diabetes of South Africa, 11(2): 80-83. 

English, R.G., Bachman, M., Bateman, E.D., Zwarenstein, M., Fairall, L.R., Bheekie, A., Majara, B.P., Lombard, C., Scherpbier, R. and Ottomani, S.E. 2006. Diagnostic accuracy of an integrated respiratory guideline in identifying patients with respiratory symptoms requiring screening for pulmonary tuberculosis: A cross-sectional study. BMC Pulmonary Medicine, 6(22). [Online]. <a href="http://www.biomedcentral.com/1471-2466/6/22" target="blank">http://www.biomedcentral.com/1471-2466/6/22</a>. 

Ferreira, M. 2006. HIV/AIDS and older people in Sub-Saharan Africa: Towards a policy framework. Global Ageing: Issues and Action, 4(2): 56-71. 

Ferreira, M. 2006. The differential impact of social-pension income on household poverty alleviation in three South African ethnic groups. Ageing and Society, 26: 337-354. 

Ferreira, M. and Kowal, P. 2006. A minimum data set on ageing and older persons in Sub-Saharan Africa: Process and outcome. African Population Studies, 21(1): 19-36. 

Gambert, S., Vergely, C., Filomenko, R., Moreau, D., Bettaieb, A., Opie, L.H. and Rochette, L. 2006. Adverse effects of free fatty acid associated with increased oxidative stress in postischemic isolated rat hearts. Molecular and Cellular Biochemistry, 283(1-2): 147-152. 

Gaziano, T.A., Weinstein, M.C. and Opie, L.H. 2006. Cardiovascular disease prevention with A multi-drug regimen in the developing world: A cost-effectiveness analysis. Lancet, 368: 679-686. 

Geffen, L. and Kalula, S.Z. 2006. Common upper respiratory tract problems in the elderly - A guide to clinical diagnosis and prudent prescription. South African Family Practice, 48(5): 20-23. 

Goedecke, J.H., Wakes, D.J., Levitt, N.S., Lambert, E.V., Collins, M., Morton, N.M., Andrew, R., Seckl, J.R. and Walker, B.R. 2006. Glucocorticoid metabolism within superficial subcutaneous rather than visceral adipose tissue is associated with features of the metabolic syndrome in South African women. Clinical Endocrinology, 65: 81-87. 

Holmes, C.B., Wood, R., Badri, M., Zilber, S., Wang, B., Maartens, G., Zheng, H., Lu, Z., Freedberg, A. and Losina, E. 2006. CD4 decline and incidence of opportunistic infections in Cape Town, South Africa: Implications for prophylaxis and treatment. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 42(4): 464-469. 

How, O.J., Aasum, E., Severson, D.L., Chan, W.Y.A., Essop, M.F. and Larsen, T.S. 2006. Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice. Diabetes, 55: 466-473. 

Imrie, H., Connell, J., Freel, M., Mayosi, B.M., Davies, E., Fraser, R., Ingram, M., Cordell, H.J., Farrall, M., Avery, P.J., Watkins, H. and Keavney, B. 2006. Association between aldosterone production and variation in the 11Beta-hydroxylase (CYP11B1) gene. Journal of Clinical Endocrinology and Metabolism, 91(12): 5051-5056. 

Jaspan, H.B., Berwick, J., Myer, L., Mathews, C., Flisher, A.J., Wood, R. and Bekker, L.G. 2006. Adolescent HIV prevalence, sexual risk, and willingness to participate in HIV vaccine trials. Journal of Adolescent Health, 39(5): 342-648. 

Jessop, S.J. 2006. HIV-associated Kaposi's sarcoma. Dermatologic Clinics, 24: 509-520. 

Juniper, E.F., Bousquet, J., Abetz, L. and Bateman, E.D. 2006. Identifying 'well-controlled' and 'not well-controlled' asthma using the Asthma Control Questionnaire. Respiratory Medicine, 100: 616-621. 

Kalula, S.Z., De Villiers, L., Ross, K. and Ferreira, M. 2006. Management of older patients presenting after a fall - an accident and emergency department audit. South African Medical Journal, 96(8): 718-721. 

Kaplan, N.M. and Opie, L.H. 2006. Controversies in hypertension. Lancet, 367: 168-176. 

Khumalo, N.P. 2006. African hair length: The picture is clearer. Journal of the American Academy of Dermatology, 54: 886-888. 

Khumalo, N.P., Jessop, S.J. and Ehrlich, R.I. 2006. Prevalence of cutaneous adverse effects of hairdressing. Archives of Dermatology, 142: 377-383. 

Khumalo, N.P., Pillay, K., Beighton, P., Wainwright, H.C., Walker, B., Saxe, N.P., Mayosi, B.M. and Bateman, E.D. 2006. Poikiloderma, tendon contracture and pulmonary fibrosis: A new autosomal dominant syndrome? British Journal of Dermatology, 155: 1057-1061. 

Kirsch, R., Clarkson, V., Verdonk, R.C., Marais, A.D., Shephard, E.G., Ryffel, B. and De lA Mare Hall, P. 2006. Rodent nutritional model of steatohepatitis: Effects of endotoxin (lipopolysaccharide) and tumor necrosis factor alpha deficiency. Journal of Gastroenterology and Hepatology, 21(1): 174-182. 

Kirsch, R., Pentecost, M., De la Mare Hall, P., Epstein, D., Watermeyer, G. and Friederich, P.W. 2006. Role of colonoscopic biopsy in distinguishing between Crohn's disease and intestinal tuberculosis. Journal of Clinical Pathology, 59: 840-844. 

Kirsch, R., Sijtsema, H., Tlali, M., Marais, A.D. and De la Mare Hall, P. 2006. Effects of iron overload in a rat nutritional model of non-alcoholic fatty liver disease. Liver International, 26(10): 1258-1267. 

Koegelenberg, C.F.N., Theron, J., Brundyn, K., Bolliger, C.T., Marais, A.D. and Diacon, A.H. 2006. A patient with a persistent pleural effusion. Respiration, 73(1): 120-123. 

Krige, J.E., Kotze, U.K., Bornman, P.C., Shaw, J.M. and Klipin, M. 2006. Variceal recurrence, rebleeding and survival after endoscopic injection with sclerotherapy in 287 alcoholic cirrhotic patients with bleeding esophageal varices. Annals of Surgery, 244: 764-770. 

Lacerda, L., Smith, R.M., Opie, L.H. and Lecour, S. 2006. TNFalpha-induced cytoprotection requires the production of free radicals within mitochondria in C92)C(12) myotubes. Life Sciences, 79: 2194-2201. 

Lawn, S.D., Bekker, L.G., Middelkoop, K., Myer, L. and Wood, R. 2006. Impact of HIV infection on the epidemiology of tuberculosis in a peri-urban community in South Africa: The need for age-specific interventions. Clinical Infectious Diseases, 42(7): 1040-7. 

Lawn, S.D., Myer, L., Bekker, L.G. and Wood, R. 2006. Burden of tuberculosis in an antiretroviral treatment programme in sub-Saharan Africa: Impact on treatment outcomes and implications for tuberculosis control. AIDS, 20(12): 1605-12. 

Lawn, S.D., Myer, L., Bekker, L.G. and Wood, R. 2006. CD4 cell count recovery among HIV-infected patients with very advanced immunodeficiency commencing antiretroviral treatment in sub-Saharan Africa. BMC Infectious Diseases, 6: 59. 

Lawn, S.D., Myer, L., Harling, G., Orrell, C., Bekker, L.G. and Wood, R. 2006. Determinants of mortality and nondeath losses from an antiretroviral treatment service in South Africa: Implications for program evaluation. Clinical Infectious Diseases, 43(6): 770-776. 

Le Riche, M., Burgess, L.J. and Marais, A.D. 2006. Pseudohyponatraemia in a patient with obstructive jaundice. Clinica Chimica Acta, 366: 357-360. 

Lecour, S., Owira, P.M.O. and Opie, L.H. 2006. Ceramide-induced preconditioning involves reactive oxygen species. Life Sciences, 78: 1702-1706. 

Lecour, S., Van der Merwe, E.L., Opie, L.H. and Sack, M.N. 2006. Ceramide attenuates hypoxic cell death via reactive oxygen species signaling. Journal of Cardiovascular Pharmacology, 47(1): 158-163. 

Lehloenya, R. and Meintjes, G. 2006. Dermatologic manifestations of the immune reconstitution inflammatory syndrome. Dermatologic Clinics, 24(4): 549-570. 

Makaula, S., Adam, T. and Essop, M.F. 2006. Upstream stimulatory factor 1 transactivates the human gene promoter of the cardiac isoform of acetyl-CoA carboxylase. Archives of Biochemistry and Biophysics, 446: 91-100.

Matolweni, L., Bardien, S., Rebello, G., Oppon, E., Munclinger, M., Ramesar, R., Watkins, H. and Mayosi, B.M. 2006. Arrhythmogenic right ventricular cardiomyopathy type 6 (ARVC6): Support for the locus assignment, narrowing of the critical region and mutation screening of three candidate genes. BMC Medical Genetics, 7(29). [Online]. <a href="http://www.biomedcentral.com/1471-2350/7/21" target="blank">http://www.biomedcentral.com/1471-2350/7/21</a>. 

Mayosi, B.M. 2006. A proposal for the eradication of rheumatic fever in our lifetime. South African Medical Journal, 96(3): 229-230.

Mayosi, B.M. 2006. Protocols for antibiotic use in primary and secondary prevention of rheumatic fever. South African Medical Journal, 96(3): 240. 

Mayosi, B.M., Robertson, K.A., Volmink, J., Adebo, W., Akinyore, K., Amoah, A., Bannerman, C., Biesman-Simons, S., Carapetis, J., Cilliers, A. and Commerford, P.J. 2006.The Drakensberg Declaration on the Control of Rheumatic Fever and Rheumatic Heart Disease in Africa. South African Medical Journal, 96(3): 246. 

Mayosi, B.M., Kardos, A., Davies, C.H., Gumedze, F.N., Hovnanian, A., Burge, S. and Watkins, H. 2006. Heterozygous disruption of SERCA2a is not associated with impairment of cardiac performance in man: Implications for SERCA2a as a therapeutic target in heart failure. Heart, 92: 102-109. 

Mayosi, B.M., Wiysonge, C.S., Ntsekhe, M., Volmink, J., Gumedze, F.N., Maartens, G., Aje, A., Thomas, B.M., Thomas, K.M., Awotedu, A.A., Thembela, B., Mntla, P., Maritz, F., Blackett, K.N., Nkouonlack, D.C., Burch, V., Rebe, K., Parish, A., Sliwa, K., Vezi, B.Z., Alam, N., Brown, B., Gould, T., Visser, T., Shey, M.S., Magula, N.P. and Commerford, P.J. 2006. Clinical characteristics and initial management of patients with tuberculous pericarditis in the HIV era: The investigation of the management of pericarditis in Africa (IMPI Africa) registry. BMC Infectious Diseases, 6(2). [Online]. <a href="http://www.biomedcentral.com/1471-2334/6/2" target="blank">http://www.biomedcentral.com/1471-2334/6/2</a>. 

McCulloch, M., Gajjar, P., Spearman, W., Burger, H., Sinclair, P., Savage, L., Morrison, C., Davies, C., Ruysch van Dugteren, G.P.A., Maytham, D., Wiggelinkhuizen, J., Pascoe, M.D., McCurdie, F.J., Pontin, A., Muller, E., Numanoglu, A., Millar, A.J.W., Rode, H. and Khan, D. 2006. Overview of a paediatric renal transplant programme. South African Medical Journal, 96(9): 955-959. 

McIlleron, H., Wash, P., Burger, A., Norman, J., Folb, P.I. and Smith, P. 2006. Determinants of Rifampin, Isoniazid, Pyrazinamide and Ethambutol pharmacokinetics in A cohort of tuberculosis patients. Antimicrobial Agents and Chemotherapy, 50(4): 1170-1177. 

Mendelson, M., Hanekom, W.A., Ntutela, S., Vogt, M.C., Steyn, L.M., Maartens, G. and Kaplan, G. 2006. Quantitative and functional differences in peripheral blood myeloid dendritic cells from patients with pleural and with parenchymal lung tuberculosis. Clinical and Vaccine Immunology, 13(12): 1299-1306. 

Micklesfield, L., Levitt, N.S., Dhansay, M.A., Norris, S., Van der Merwe, L. and Lambert, E.V. 2006. Maternal and early life influences on calcaneal ultrasound parameters and metacarpal morphometry in 7- to 9-year-old children. Journal of Bone and Mineral Metabolism, 24(3): 235-242. 

Middelkoop, K., Myer, L., Smit, J., Wood, R. and Bekker, L.G. 2006. Design and evaluation of A drama-based intervention to promote voluntary counseling and HIV testing in A South African community. Sexually Transmitted Diseases, 33(8): 524-526. 

Minghetti, L., Greco, A., Puopolo, M., Combrinck, M.I., Warden, D. and Smith, A.D. 2006. Peripheral reductive capacity is associated with cognitive performance and survival in Alzheimer's disease. Journal of Neuroinflammation, 3(4). [Online].  <a href="http://www.jneuroinflammation.com/content/3/1/4" target="blank">http://www.jneuroinflammation.com/content/3/1/4</a>. 

Moodley, I., Rayner, B.L. and Singh, D. 2006. Losartan appears cost-effective for reducing stroke in people with hypertension and left ventricular hypertrophy. Evidence-based Cardiovascular Medicine, 10: 94-95. 

Nachega, J., Knowlton, A.R., Deluca, A., Schoeman, J.H., Watkinson, L., Efron, A., Chaisson, R.E. and Maartens, G. 2006. Treatment supporter to improve adherence to antiretroviral therapy in HIV-infected South African adults. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 43(Suppl 1): S127-S133. 

Nachega, J.N., Hislop, M., Dowdy, D.W., Lo, M., Omer, S.B., Regensberg, L., Chaisson, R.E. and Maartens, G. 2006. Adherernce to highly active antiretroviral therapy assessed by pharmacy claims predicts survival in HIV-infected South African adults. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 43(1): 78-84. 

Nattel, S. and Opie, L.H. 2006. Controversies in atrial fibrillation. Lancet, 367: 62-272. 

Newton, P.N., Barnes, K.I., Smith, P., Evans, A.C., Chierakul, W., Ruangveerayuth, R. and White, N.J. 2006. The pharmacokinetics of intravenous artesunate in adults with severe falciparum malaria. European Journal of Clinical Pharmacology, 62: 1003-1009. 

Nkgudi, B., Robertson, K., Volmink, J. and Mayosi, B.M. 2006. Notification of rheumatic fever in South Africa - evidence for underreporting by health care professionals and administrators. South African Medical Journal, 96(3): 206-208. 

Obihara, C.C., Kimpin, J.L.L., Gie, R.P., Van Lill, S., Hoekstra, M.O., Marais, B.J., Schaaf, H.S., Lawrence, K., Potter, P.C., Bateman, E.D., Lombard, C. and Beyers, N. 2006. Mycobacterium tuberculosis infection may protect against allergy in A tuberculosis endemic area. Clinical and Experimental Allergy, 36: 70-76. 

Omar, H. 2006. Common skin disorders in the elderly. South African Family Practice, 48(5): 29-34. 

Opie, L.H., Commerford, P.J. and Gersh, B.J. 2006. Controversies in stable coronary artery disease. Lancet, 367: 69-78. 

Opie, L.H., Commerford, P.J., Gersh, B.J. and Pfeffer, M.A. 2006. Controversies in ventricular remodelling. Lancet, 367(9507): 356-367. 

Post, F.A., Bekker, L.G., Steyn, L.M., Ryffel, B. and Kaplan, G. 2006. Mycobacterium tuberculosis H37Ra and H37Rv differential growth and cytokine/chemokine induction in murine macrophages in vitro. Journal of Interferon and Cytokine Research, 26(1): 27-33. 

Rawoot, A., Little, F. and Heckman, J. 2006. Risk of malignancy in myasthenia gravis patients exposed to azathioprine therapy for a median period of 3 years. South African Medical Journal, 96(12): 1249-1251. 

Rayner, B.L. and Becker, P. 2006. The prevalence of microalbuminuria and ECG left ventricular hypertrophy in hypertensive patients in private practices in South Africa. Cardiovascular Journal of South Africa, 17: 245-249. 

Rayner, B.L., Trinder, Y., Baines, D., Isaacs, S. and Opie, L.H. 2006. Effect of losartan versus candesartan on uric acid, renal function and fibrinogen in patients with hypertension and hyperuricemia associated with diuretics. American Journal of Hypertension, 19: 208-213. 

Razeghi, P., Baskin, K.S., Sharma, S., Young, M.E., Stepkowski, S., Essop, M.F. and Taegtmeyer, H. 2006. Atrophy, hypertrophy, and hypoxemia induce transcriptional regulators of the ubiquitin proteasome system in the rat heart. Biochemical and Biophysical Research Communications, 342: 361-364. 

Robertson, K.A., Volmink, J. and Mayosi, B.M. 2006. Towards a uniform plan for the control of rheumatic fever and rheumatic heart disease in Africa - the Awareness Surveillance Advocacy Prevention (ASAP) Programme. South African Medical Journal, 96(3): 241-245. 

Schaars, C.F., Meintjes, G., Morroni, C., Post, F.A. and Maartens, G. 2006. Outcome of AIDS-associated cryptococcal meningitis initially treated with 200 mg/day or 400 mg/day of fluconazole. BMC Infectious Diseases, 6(118). [Online]. http://www.biomedcentral.com/1471-2334/6/118. 

Seedat, Y.K., Croasdale, M.A., Milne, F.J., Opie, L.H., Pinkney-Atkinson, V.J. and Rayner, B.L. 2006. South African Hypertension Guideline 2006. South African Medical Journal, 96(4): 337362. 

Seggie, J.L. and Burch, V. 2006. The power of patient-side teaching - still of benefit to student and patient. South African Medical Journal,96(5): 424-426. 

Semple, P.L., Fieggen, A.G., Parkes, J. and Levitt, N.S. 2006. Giant prolactinomas in adolescence: An uncommon cause of blindness. Child's Nervous System, 23(2): 213-217. 

Simpson, J.A., Agbenyega, T., Barnes, K.I., Di Perri, G., Folb, P.I., Gomes, M., Krishna, S., Krudsood, S.A., Looareesuwan, S., Mansor, S., Mcilleron, H., Miller, R., Molyneux, M., Mwenechanya, J., Navaratnam, V., Nosten, F., Olliaro, P., Pang, L. and Ribeiro, I. 2006. Population pharmacokinetics of Artesunate and Dihydroartemisin in following intra-rectal dosing of artesunate in malariA patients. PLoS Medicine, 3(11): 2113-2123. 

Smedema, E., Mayosi, B.M. and Smedema, J.P. 2006. Hydatid disease - the "water lily" sign. South African Medical Journal, 96(10): 1042-1043. 

Smit, J., Middelkoop, K., Myer, L., Seedat, S., Bekker, L.G. and Stein, D.J. 2006. Willingness to participate in HIV vaccine research in a peri-urban South African community. International Journal of STD & AIDS, 17: 1-5. 

Smit, J., Middelkoop, K., Myer, L., Seedat, S., Wood, R., Stein, D.J. and Bekker, L.G. 2006. Sexual risk factors associated with volunteering for HIV vaccine research in South Africa. AIDS Care, 18: 569-573. 

Smit, J., Myer, L., Middelkoop, K., Seedat, S., Wood, R., Bekker, L.G. and Stein, D.J. 2006. Mental health and sexual risk behaviours in a South African township: A community-based cross-sectional study. Public Health, 120(6): 534-42. 

Smit, J., Van den Berg, C.E., Bekker, L.G., Stein, D.J. and Seedat, S. 2006. Translation and cross-cultural adaptation of a mental health battery in an African setting. African Health Sciences, 6: 215-222. 

Spearman, W., McCulloch, M., Millar, A.J.W., Burger, H., Numanoglu, A., Goddard, E., Gajjar, P., Davies, C., Muller, E., McCurdie, F.J., Kemm, D., Cywes, S., Rode, H. and Kahn, D. 2006. Liver transplantation at Red Cross War Memorial Children's Hospital. South African Medical Journal, 96(9): 960-963. 

Sreenivasan, G. and Benatar, S.R. 2006. Challenges for global health in the 21st century: Some upstream considerations. Theoretical Medicine and Bioethics, 27(1): 3-11. 

Thomas, J.M., McCulloch, M., Spearman, W., Butt, A.D. and Numanoglu, A. 2006. A practical approach to anaesthesia for paediatric liver transplantation. Southern African Journal of Anaesthesia and Analgesia, 12(3): 11-15. 

Timm, J., Kurepina, N., Kreiswirth, B.N., Post, F.A., Walther, G., Wainwright, H.C., Bekker, L.G., Kaplan, G. and Mckinney, J.D. 2006. A multidrug-resistant, acr1-deficient clinical isolate of Mycobacerium tuberculosis is unimpaired for replication in macrophages. Journal of Infectious Diseases, 193: 1703-10. 

Tipping, B. and De Villiers, L. 2006. Pneumonia in the elderly - diagnosis and treatment in general practice. South African Family Practice, 48(5): 24-28. 

Tipping, B., De Villiers, L., Candy, S. and Wainwright, H.C. 2006. Stroke caused by Human Immunodeficiency Virus-associated intracranial large-vessel aneurysmal vasculopathy. Archives of Neurology, 63: 1640-1642. 

Tipping, B., Kalula, S.Z. and Badri, M. 2006. The burden and risk factors for adverse drug events in older patients - a prospective cross-sectional study. South African Medical Journal, 96(12): 1255-1259. 

Todd, G. 2006. Adverse cutaneous drug eruptions and HIV: A clinician's global perspective. Dermatologic Clinics, 24: 459-472.

Tuunanen, H., Engblom, E., Naum, A., Nagren, K., Hesse, B., Airaksinen, K.E., Nuutila, P., Iozzo, P., Ukkonen, H., Opie, L.H. and Knuuti, J. 2006. Free fatty acid depletion acutely decreases cardiac work and efficiency in cardiomyopathic heart failure. Circulation, 114: 2130-2137. 

Van der Graaf, A., Nierman, M.C., Firth, J.C., Wolmarans, K.H., Marais, A.D. and De Groot, E. 2006. Efficacy and safety of fluvastatin in children and adolescents with heterozygous familial hypercholesterolemia. Acta Paediatrica, 95(11): 1461-1466. 

Van der Merwe, S.W., Conradia, M.M., Bond, R., Olivier, B.J., Fritz, E., Nieuwoudt, M., Delport, R., Slavik, T., Engelbrecht, G.H.C., Kahn, D., Shephard, E.G., Kotze, M., De Villieres, N. and Hough, S. 2006. Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting. World Journal of Gastroenterology, 12(28): 4504-4510. 

Wallis, L.A., Gottschalk, S.B., Wood, D., Bruijns, S., De Vries, S. and Balfour, C.H. 2006. The Cape Triage Score - a triage system for South Africa. South African Medical Journal, 96(1): 53-56. 

Wilkins, J., Langdon, G., McIlleron, H., Pillai, G.C., Smith, P. and Simonsson, U.S.H. 2006. Variability in the population pharmacokinetics of pyrazinamide in South African tuberculosis patients. European Journal of Clinical Pharmacology, 62: 727-735. 

Wilmshurst, J., Blockman, M., Argent, A.C., Gordon-Graham, E., Thomas, J.M., Whitelaw, A.C., McCulloch, M., Ramiah, M., Dyeshana, H. and Ireland, J.D. 2005. Leaving the party - withdrawal of South African essential medicines. South African Medical Journal, 95(5): 419. 

Wilson, D.P.K., Nachega, J.N., Morroni, C., Chaisson, R.E. and Maartens, G. 2006. Diagnosing smear-negative tuberculosis using case definitions and treatment response in HIV-infected adults. International Journal of Tuberculosis and Lung Disease, 10(1): 31-38. 

Yellon, D.M. and Opie, L.H. 2006. Postconditioning for protection of the infarcting heart. Lancet, 367: 456-458. 

Yoon, D.Y., Scott, K., Hill, M.N., Levitt, N.S. and Lambert, E.V. 2006. Review of three tests of motor proficiency in children. Perceptual and Motor Skills, 102(2): 543-551. 

Yusuf, S., Mehta, S.R., Bassand, J.P., Budaj, A., Ntshekhe, M. and Chrolavicius, S. 2006. Comparison of fondaparinux and enoxaparin in acute coronary syndromes. New England Journal of Medicine, 354: 464-476. 

Zar, H.J., Langdon, G., Apolles, P.C., Eley, B.S., Hussey, G.D. and Smith, P. 2006. Oral trimethoprim-sulphamethoxazole levels in stable HIV-infected children. South African Medical Journal, 96(7): 627-629. 

Zungu, M., Felix, R. and Essop, M.F. 2006. Wy-14,643 and fenofibrate inhibit mitochondrial respiration in isolated rat cardiac mitochondria. Mitochondrion, 6: 315-322. 

CHAPTERS IN BOOKS 

Benatar, S.R. 2006. Economics of health in South Africa: Past, present and future. In A. Carmi and D. Nachshon (eds), Medical law 1980-2005: Look back with a view to the future: 249-262. Israel: Yozmot Publishing Ltd. 

Benatar, S.R. 2006. Ethics and public health: A view from the South. In J.R. Texidor (ed.), Public health: The challenges of a new century: 93-100. Spain: Fundacion BBVA. 

Benatar, S.R. 2006. Global health ethics: The rationale for mutual caring. In B. Bennett (ed.), Health, rights and globalization: 107-138. UK: Ashgate Press. 

Benatar, S.R. 2006. South Africa's transition in a globalising world: HIV/AIDS as a window and a mirror. In B. Bennett (ed.), Health, rights and globalization: 347-375. UK: Ashgate Press. 

Connor, M. and Bryer, A. 2006. Stroke in South Africa. In J.M. Fourie, N. Temple and K. Steyn (eds), Chronic diseases of lifestyle in South Africa: 1995-2005: 195-204. Cape Town: SA Medical Research Council. 

Levitt, N.S., Lambert, E.V. and Norris, S. 2006. Early life origins of adult chronic diseases: A South African perspective. In J.M. Fourie, N. Temple and K. Steyn (eds), Chronic diseases of lifestyle in South Africa 1995-2005: 58-64. Cape Town: SA Medical Research Council. 

Mollentze, W.F. and Levitt, N.S. 2006. Diabetes mellitus and impaired glucose tolerance in South Africa. In J.M. Fourie, N. Temple and K. Steyn (eds), Chronic diseases of lifestyle in South Africa: 1995-2005: 109-121. Cape Town: Sa Medical research Council. 

Opie, L.H. 2006. Calcium channel blockers: Controversies, lessons and outcomes. In R.A. O'Rourke, V. Fuster and W. Alexander (eds), Hypertension, companion to Brenner & Rector's The Kidney, 2nd Edition: 408-415. Philadelphia: Elsevier. 

Steyn, K. and Levitt, N.S. 2006. Health services research in South Africa for chronic diseases of lifestyle. In J.M. Fourie, N. Temple and K. Steyn (eds), Chronic diseases of lifestyle in South Africa: 1995-2005: 226-248. Cape Town: SA Medical Research Council. 

PEER-REVIEWED PUBLISHED CONFERENCE PROCEEDINGS 

Brown, S.L., De Jager, D., Wood, R. and Rivett, U.K. 2006. A pharmacy stock control management system to effectively monitor and manage patients on ART. Proceedings of the 4th IEE Seminar on Appropriate Healthcare Technologies for Developing Countries, 23-24 May 2006, London, United Kingdom, 29-35. ISBN 0-86341-633-0. 

Spottiswoode, B., Spottiswoode, B.S., Zhong, X., Lorenz, C.H., Mayosi, B.M., Meintjes, E.M. and Epstein, F.H. 2006. Motion-guided segmentation of the left ventricle for cine DENSE MRI. Proceedings of the 14th Scientific Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), 6-12 May 2006, Seattle, Washington, USA, 794. ISSN 1545-4428. [CD-ROM]. 

Spottiswoode, B., Spottiswoode, B.S., Zhong, X., Patel, R.A., Helm, P.A., Mayosi, B.M., Kramer, C.M., Meintjes, E.M. and Epstein, F.H. 2006. Measuring LV-RV interventricular dyssynchrony using cine DENSE MRI. Proceedings of the 14th Scientific Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), 6-12 May 2006, Seattle, Washington, USA, 148. ISSN 1545-4428. [CD-ROM]. 

NON PEER-REVIEWED PUBLISHED CONFERENCE PROCEEDINGS 

Bekker, L.G., Middelkoop, K., Myer, L., Lawn, S.D., Grant, A.D., Kaplan, G. and Wood, R. 2006. Undiagnosed culture positive tuberculosis in a periurban community in South Africa. Proceedings of International AIDS Conference, Toronto, Canada, CDB0250. 

Bekker, L.G., Middelkoop, K., Myer, L., Whitelaw, A.C., Grant, A.D., Kaplan, G., Lawn, S.D. and Wood, R. 2006. Prevalence of HIV and Undiagnosed Tuberculosis in A Peri-urban Community in South Africa. Proceedings of Conference on Retroviruses and Opportunistic Infections, Denver, Colorado, USA, 69. 

Lawn, S.D., Myer, L., Bekker, L.G. and Wood, R. 2006. Prevalence and incidence of tuberculosis in an antiretroviral treatment (ART) programme in South Africa: risk factors and impact on ART outcomes. Proceedings of International AIDS Conference, Toronto, Canada, MOPE0175. 

Lawn, S.D., Myer, L., Harling, G., Orrell, C., Bekker, L.G. and Wood, R. 2006. Evaluation of mortality and other programme losses in a community-based antiretroviral programme in South Africa. Proceedings of International AIDS Conference, Toronto, Canada, THPE0191. 

Middelkoop, K., Myer, L., Mthimunye, S., Smit, J., Wood, R. and Bekker, L.G. 2006. High HIV incidence and retention rates within an HIV vaccine preparedness cohort in Cape Town, South Africa. Proceedings of International AIDS Conference, Toronto, Canada, MOPE0423. 

Mohammed, A., Myer, L., Ehrlich, R.I., Wood, R., Cilliers, F. and Maartens, G. 2006. Randomized controlled trial of isoniazid preventive therapy, administered by patient-nominated supervisors, in advanced HIV disease. Proceedings of International AIDS Conference, Toronto, Canada, MOPE0185. 

PUBLISHED CONFERENCE ABSTRACTS 

Bryer, A., Tipping, B. and De Villiers, L. 2006. Health in transition: stroke profile in A South African urban population. International Journal of Stroke, 1(Suppl 1): 29. 

Chalmers, D.A., Williams, H.C., Todd, G., Saxe, N.P., Milne, J., Tolosana, S., Ngcelwane, P.N., Hlaba, B.N., Mngomeni, L.N. and Nonxuba, T.G. 2006. Validation of the United Kingdom Working Party diagnostic criteria for atopic eczema in an African setting. British Journal of Dermatology, 155(Supplement 1) : 5. 

Colven, R. and Todd, G. 2006. A teledermatology network for undeserved areas of South Africa. Journal der Deutschen Dermatologischen Gesellschaft, 4(11): 1001. 

Dawson, R., Condos, R., Lucke, W., Ress, S.R., Raju, B., Bateman, E.D. and Rom, W.N. 2006. Randomized clinical trial of aerosol or subcutaneous interferon gamma plus DOTS alone for cavitary tuberculosis: early results. Proceedings of the American Thoracic Society 3 (April) : A745. 

De Villiers, L., Kalula, S.Z. and Burch, V. 2006. Can a multidisciplinary Stroke Unit function in Sub-Saharan Africa? International Journal of Stroke, 1(Suppl 1): 25. 

De Villiers, L., Kalula, S.Z., Bryer, A. and Ferreira, M. 2006. Stroke outcomes in Sub-Saharan Africa. International Journal of Stroke, 1(Suppl 1): 25. 

Epstein, D., Dave, J., Albaquerque-Jonathan, G., Levitt, N.S., Watermeyer, G., Fataar, A.B. and Metz, D.C. 2006. Vertebral fracture risk factors in inflammatory bowel disease (IBD) patients at Groote Schuur Hospital, Cape Town. South African Medical Journal, 96(8): 738. 

Epstein, D., Watermeyer, G., Hlatshwayo, S., Levin, D. and Winter, T.A. 2006. Immunosuppression therapy for ulcerative colitis at Groote Schuur Hospital. South African Medical Journal, 96 (8): 730. 

Ferreira, M. 2006. Ageing in Africa in the 21st Century: Challenges and opportunities for adjustment. Gerontology, June 26-30: 386-387. 

Ferreira, M. 2006. HIV/AIDS and older people in Africa: What policies and provisions? International Federation on Ageing (IFA) 8th Global Conference 30 May - 2 June: 122. 

Jeebhay, M., Robins, T., Malo, J.L., Lin, X., Seixas, N., Lehrer, S., Bateman, E.D., Baatjies, R., Miller, M., George, D., Russford, E., Smuts, M. and Lopata, A.L. 2006. Risk factors for occupational allergy and asthma among fish processing workers in South Africa. Conference on Research on workplace health and safety: from the core to the margins - mini symposium on occupational allergy and asthma among seafood processing workers.Memorial University, St Johns, Newfoundland / Labrador, Canada, June 2006. Abstract and invited speaker. 

Kalula, S.Z. 2006. Challenges of a memory clinic in an African country. The Internation Federation on Ageing (IFA) 8th Global Conference 30 May - 2 June 2006: 93. 

Kalula, S.Z., De Villiers, L., Ross, K. and Ferreira, M. 2006. Challenges of access to and assessment in a Memory Clinic in a developing country. Gerontology, 26-30 June: 642. 

Levin, D., Mohamed, N., Watermeyer, G., Epstein, D., Hlatshwayo, S. and Metz, D.C. 2006. A quality assurance evaluation of a locally produced rapid urease test (RUT) for the diagnosis of Helicobacter pylori infection in Cape Town. South African Medical Journal, 96(8): 734. 

Levin, D., Watermeyer, G., Hlatshwayo, S., Epstein, D., Bardham, K.D. and Metz, D.C. 2006. Age and alarm symptoms as an indication for endoscopy in a resource limited environment. Gastroenterology, 130(4): A627. 

Semple, P.L., Brauns, C., Dawson, R., Bateman, E.D., Krensky, A.M., Condos, R., Rom, W.N. and Ress, S.R. 2006. Impact of DOTS and IFN-gamma on cytolytic mediator expression in pulmonary TB. Proceedings of the American Thoracic Society 3 (April): A219. 

Shaw, J.M., Bornman, P.C., Callanan, M.D. and Metz, M.D. 2006. Longterm (6 year) outcome of Laparascopic Nissen and Toupet Fundoplication. Gasteroenterol, 130(2): A-878. 

Spottiswoode, B., Spottiswoode, B.S., Zhong, X., Lorenz, C.H., Meintjes, E.M., Mayosi, B.M. and Epstein, F.H. 2006. Tracking 3D Myocardial motion using slice-followed Cine-DENSE . Journal of Cardiovascular Magnetic Resonance, 8(1): Page 80. Abstract # 187. 

Tipping, B., De Villiers, L., Candy, S., Wainwright, H.C. and Bryer, A. 2006. Vasculopathy in HIV infected patients with stroke. International Journal of Stroke, 1(Suppl 1): 39-40. 

Wiysonge, C.S., Ntshekhe, M., Gumedze, F.N., Maartens, G., Volmink, J., Commerford, P.J. and Mayosi, B.M. 2006. Excess mortality in presumed tuberculous pericarditis. European Heart Journal, 27: 958. 

THESES AND DISSERTATIONS PASSED FOR HIGHER DEGREES 

English, R.G. 2006. The development and validation of a respiratory guideline for nurses in primary care in South Africa: 1-297. PhD. 

Ntsekhe, M. 2006. The investigation of the management of tuberculous pericarditis in Africa (IMPI Africa) project: rationale, designe and baseline characteristics of participants in a multicentre registry of suspected tuberculous pericarditis: 1-30. MPhil. 

UNIVERSITY PUBLICATIONS AND WORKS OF A POPULAR NATURE 

Adams, B.K., Mann, M.D., Aboo, A., Isaacs, S. and Evans, A.C. 2006. The effects of sorbitol on gastric emptying half-times and small intestinal transit after drug overdose (letter). American Journal of Emergency Medicine, 24: 130-138. 

Blackhurst, D.M. and Marais, A.D. 2006. Uitwerking van alkoholverbruik op gesondheid: oorsig. Wineland July 2006: 65-66. 

Commerford, P.J. 2006. Optimal revascularisation. South African Heart Journal, July 2006: 5-10. 

Commerford, P.J. and Mayosi, B.M. 2006. Acute rheumatic fever. Medicine 34: 239-243. 

Ferreira, M. 2006. Geriatric medicine in South Africa - a Cinderella subspecialty? South African Family Practice 48 (5): 35-41. 

Isiavwe, A.R., Ross, I.L., Duffield, M., Semple, P.L. and Levitt, N.S. 2006. An unusual case of acromegaly. Case report. CME 24 (9): 533-534. 

Kies, B.M. 2006. First time seizures. MIMS Disease Review: 374-377. 

Kies, B.M. 2006. How to perform a brief, appropriate neurological examination. South African Family Practice Manual: 40-42. 

Majikela-Dlangamandla, C., Isiavwe, A.R. and Levitt, N.S. 2006. Diabetes monitoring in developing countries. Diabetes Voice 51 (November): 28-31. 

Mamabolo, R.L., Alberts, M., Steyn, N.P. and Levitt, N.S. 2006. The effect of maternal glucose metabolism, iron, vitamin B12 and folate status on pregnancy outcomes. SAJCN 19 (3): 120-130. 

Mayosi, B.M. 2006. The Colleges of Medicine of South Africa marks 50 years of excellence in postgraduate medical and dental education. Transactions of the Colleges of Medicine of South Africa 50 (1): 28. 

Mayosi, B.M. 2006. The right medicine. Financial Mail 5 May 2006: 34. 

Ntsekhe, M. and Mayosi, B.M. 2006. Infectious diseases of the heart. CME 24: 189-193. 

Raal, F.J. and Marais, A.D. 2006. Adoption of the European Guidelines to cardivascular prevention in clinical practice - guide to lipid management. South African Heart Journal 3 (July supplement): 3. 

Rayner, B.L. 2006. Angiotensin receptor blockers in cardiovascular disease. MIMS Disease Review, 41: 42a-43a. 

Rayner, B.L. 2006. Hypertension lifestyle management. Modern Medicine, 31: 70-72. 

Semple, P.L., Ross, I.L., Duffield, M., Levitt, N.S. and Isiavwe, A.R. 2006. An unusual case of acromegaly. CME, 24(9): 533-534. 

ONLINE WORKS 

Rayner, B.L. 2006. La evaluacion de la lesion de organo blanco por radiografia de torax en pacientes hipertensos es un metodo costoefectivo (The chest radiograph: an underutilised investigation in hypertensive patients).  <a href="http://www.siicsalud.com/dato/dat049/06818007.htm" target="blank">http://www.siicsalud.com/dato/dat049/06818007.htm</a>. 

EXTENSION AND DEVELOPMENT WORK 

Connor, M. and Bryer, A. 2006. Stroke in South Africa. In: Chronic Diseases of Lifestyle in South Africa 1995-2005. SA Medical Research Council. Dept of Neurology, UCT.